Friday, 29/08/2008

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HGSI


LymphoStat-B™ | HGS-ETR1 | HGS-ETR2 | ABthrax™ |

In 1999/2000 CAT entered into two research agreements with Human Genome Sciences Inc (HGSI) from which four human monoclonal antibody drug candidates are now in clinical development.


MedImmune Cambridge-derived Clinical Development
Partners Product Target Disease PreC  PhI PhII PhIII Fld Mkt
HGSI LymphoStat-B™ BLyS systemic lupus erythematosus            
HGSI LymphoStat-B™ BLyS rheumatoid arthritis            
HGSI HGS-ETR1 TRAIL-R1 non small-cell lung cancer            
HGSI HGS-ETR1 TRAIL-R1 non Hodgkin's lymphoma            
HGSI HGS-ETR1 TRAIL-R1 advanced colorectal cancer            
HGSI HGS-ETR1 TRAIL-R1 myeloma (+chemotherapy)            
HGSI HGS-ETR1 TRAIL-R1 solid tumours (+ chemotherapy)            
HGSI HGS-ETR1 TRAIL-R1 advanced solid tumours            
HGSI HGS-ETR2 TRAIL-R2 advanced solid tumours            
HGSI ABthrax™ b.anthracis anthrax infection            

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