HGSI
In 1999/2000 CAT entered into two research agreements with Human Genome Sciences Inc (HGSI) from which four human monoclonal antibody drug candidates are now in clinical development.
MedImmune Cambridge-derived Clinical Development
| Partners |
Product |
Target |
Disease |
PreC |
PhI |
PhII |
PhIII |
Fld |
Mkt |
| HGSI |
LymphoStat-B™ |
BLyS |
systemic lupus erythematosus |
|
|
|
|
|
|
| HGSI |
LymphoStat-B™ |
BLyS |
rheumatoid arthritis |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
non small-cell lung cancer |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
non Hodgkin's lymphoma |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
advanced colorectal cancer |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
myeloma (+chemotherapy) |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
solid tumours (+ chemotherapy) |
|
|
|
|
|
|
| HGSI |
HGS-ETR1 |
TRAIL-R1 |
advanced solid tumours |
|
|
|
|
|
|
| HGSI |
HGS-ETR2 |
TRAIL-R2 |
advanced solid tumours |
|
|
|
|
|
|
| HGSI |
ABthrax™ |
b.anthracis |
anthrax infection |
|
|
|
|
|
|
Key to table