Antibody Therapeutics

Antibody therapeutics act by mimicking and harnessing the body's immune system with the antibody working as the drug molecule. Monoclonal antibodies can be used in three main therapeutic approaches:

Blocking cell activity and/or modulating immune function to prevent certain cell responses – applicable in autoimmune disorders, inflammation, allergic reactions and cancer. Examples of MedImmune Cambridge-derived antibodies in this category are HUMIRA^®, ABT-874, CAT-354, GC-1008 and MYO-029.
Activating cell activity and modulating immune functions to stimulate a desired immune response applicable in, for example, certain oncology indications. Examples of CAT-derived antibodies in this group are HGS-ETR1 and HGS-ETR2.
Delivering molecules/agents to specific cells and tissues. Examples of CAT-owned antibodies in this group are CAT-3888, and CAT-8015.

To see the MedImmune Cambridge-derived clinical pipeline, please click on the icon below: